This innovative book focuses on HDL and its relationships to triglyceride-rich particles. It is an excellent resource for educating physicians and scientists about dyslipidemia and HDL metabolism, including many exogenous substances which interact with and influence HDL.

This bibliography is organized into sections on background; relationship of high density lipoprotein, triglyceride, and coronary heart disease; genetics and genetic syndromes; secondary causes of high triglyceride and low high density lipoprotein; measurement of high density lipoprotein and triglyceride; evidence from clinical trials; approach to high triglyceride and low high density lipoprotein; and monographs.

A complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical value. This book summarizes the current state of knowledge in the field, providing for the first time a comprehensive, systematic, stylistically coherent, and up-to-date review of the composition, structure, heterogeneity, metabolism, epidemiology, genetics, and function of HDL. Divided into three main parts, High-Density Lipoproteins first examines normal HDL particles, then describes defective HDL, and finally addresses the therapeutic normalization of subnormal levels and defective biological activities of this lipoprotein class. The book highlights the functional properties of HDL, which are relevant to the pathophysiology of atherosclerosis and thrombosis, and discusses the compositional and metabolic heterogeneity of HDL particles. Readers will come away with a clear understanding of the role of HDL in biological processes, the potential value of functional HDL as a therapeutic target, and how current and emerging therapies are poised to influence the treatment of heart disease in the future.

The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol. - Provides bench-to-bedside coverage of HDL with thorough coverage of basic science, genetics, epidemiology, and treatment - Presents a complete update with six new chapters on the latest advances in HDL cholesterol research with international perspective - New chapters on proteomics, clinical impact of LCAT in HDL metabolism, and an in-depth discussion of potential targets to modify HDL provide a translational reference for clinicians

The first comprehensive text on dyslipidemia from a major academic institution, this book covers all aspects of dyslipidemia as it relates to human disease, including coronary artery disease, cerebrovascular disease, peripheral vascular disease, and pancreatitis. The material is presented in a clinician-friendly format and includes references for additional reading. Reflecting current guidelines from the National Cholesterol Education Program, the book explains why, when, and how to treat dyslipidemia. Coverage includes dietary treatment, drug treatment, and recommendations for special populations such as patients with coronary heart disease, patients at high risk for coronary heart disease, patients with diabetes, women, older adults, young adults, and racial and ethnic groups.

Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment.

Co-Published with the National Association of Clinical Nurse Specialists (NACNS) to provide you with invaluable guidance for acing your Adult-Gerontology CNS exam! This comprehensive review manual provides the ultimate resource for either the AACN Adult-Gerontology Clinical Nurse Specialist Wellness Through Acute Care (ACCNS-AG) or the ANCC Adult-Gerontology Clinical Nurse Specialist (AGCNS-BC) certification exam. It incorporates both current test plans and the most recent NACNS core competencies, encompassing all the essential knowledge you need to pass the exam and succeed in practice. Written by certified Clinical Nurse Specialist educators and practitioners, this guide begins with an overview of both exams, study tips, and test-taking strategies to help you prepare for the big day. The manual is then organized into three sections according to the Three Spheres of Impact for CNS Practice. Patient Direct Care: covers health assessment, diagnostic reasoning, pharmacology, and pathophysiology Nurses & Nursing Practice: reviews health maximization, consultation, advocacy, culturally competent care, and coaching and mentoring Organizations & Systems: features sections on leadership, QI/safety, outcomes, research, and evidence-based practice Adult-Gerontology Clinical Nurse Specialist Certification Review provides a targeted, systematic review for the ACCNS-AG and AGCNS-BC exams with end-of-chapter review questions and a FULL practice test that includes answers and rationales in an easy-to-digest format. Key Features: Reflects the latest AACN and ANCC test plans Incorporates the updated NACNS Core Competencies and the AACN Scope and Standards for CNS Practice Edited and authored by certified Clinical Nurse Specialist educators and practitioners Includes end-of-chapter review questions, PLUS a valuable 175-question practice test with rationales for self-assessment Purchase includes digital access for use on most mobile devices or computers

Manage cardiovascular problems more effectively with the most comprehensive resource available! A trusted companion to Braunwald's Heart Disease, Cardiovascular Therapeutics, 4th Edition addresses pharmacological, interventional, and surgical management approaches for each type of cardiovascular disease. This practical and clinically focused cardiology reference offers a balanced, complete approach to all of the usual and unusual areas of cardiovascular disease and specific therapies in one concise volume, equipping you to make the best choices for every patient. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Understand current approaches to treating and managing cardiovascular patients for long-term health, for complex problems, and for unusual cardiac events. Benefit from the substantial experience of Elliott M. Antman, MD, Marc S. Sabatine, MD, and a host of other respected authorities, who provide practical, evidence-based rationales for all of today's clinical therapies. Expand your knowledge beyond pharmacologic interventions with complete coverage of the most effective interventional and device therapies being used today. Easily reference Braunwald's Heart Disease, 9th Edition for further information on topics of interest. Make the best use of the latest genetic and molecular therapies as well as advanced therapies for heart failure. Cut right to the answers you need with an enhanced focus on clinically relevant information and a decreased emphasis on pathophysiology. Stay current with ACC/AHA/ESC guidelines and the best ways to implement them in clinical practice. Get an enhanced visual perspective with an all-new, full-color design throughout.

This 2 volume set comprises of the 3rd edition of Volume 1 and the 4th edition of Volume 2, both published in 2014. In recent years, we've developed a much better grasp of the factors associated with the development of obesity. New clinical trials, discoveries related to drug use, and greater understanding of the benefits of weight loss in obese patients have expanded the field of research in this area. Reflecting our evolving understanding of causes and consequences, this two-volume set examines the history and prevalence of obesity and explores its biological, behavioral, environmental, social, and cultural determinants. It discusses the consequences of obesity, prevention, evaluation of the overweight patient, and a range of treatment options, including behavior modification, diet, exercise, medications, and surgical procedures.

Principles of Gender-Specific Medicine examines how normal human biology differs between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men, and as well conditions that predominantly occur in women. Among the subjects covered are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases.* Gathers important information in the field of gender-based biology and clinical medicine, proving that a patient's sex is increasingly important in preventing illness, making an accurate diagnosis, and choosing safe and effective treatment of disease* Addresses gender-specific areas ranging from organ transplantation, gall bladder and biliary diseases, to the epidemiology of osteoporosis and fractures in men and women* Many chapters present questions about future directions of investigations