We are very pleased to put forth the first edition of 'Laboratory Manual of Pharmaceutics'. We have made this manual student friendly and relevant in terms of achieving curriculum outcome. Now, we believe that the manual has been fulfilling the aspirations of pharmaceutics teachers and students too. This manual is prepared as per PCI Education Regulations, 2014 for Degree Course in Pharmacy. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, theory, resources used, procedure, precautions, labeling, observations, result, conclusion, references and synopsis questions. The procedures and formulas of all the experiments are reviewed and added, so that the advancement in the methods can be addressed. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various topics of Pharmaceutics. The manual mainly includes the experiments through which the students will learn to prepare various types of conventional dosage forms such as syrups, elixirs, solutions, suspensions, emulsions, powders, suppositories, ointments, gargles and mouth washes in the laboratory. A brief introduction to various dosage forms before the related experiments can assist in better perception of the experiment. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. Hope this manual will help the students to learn the concept, principles and perform the experiments virtually. We wish you all the best!!!

We are very pleased to put forth the first edition of 'Laboratory Manual of Physical Pharmaceutics I'. This manual is prepared as per PCI Education Regulations, 2014 for Degree Course in Pharmacy. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various experiments in Physical Pharmaceutics I. The manual mainly includes the experiments through which the students will learn how the basic properties of drug like solubility, dissolution, can limit the bioavailability of drug and in turn the efficacy of the drug. The solubility enhancement techniques like reduction of particle size, use of solubilizing agents or prodrugs etc. are also discussed. The students will also learn about the importance of drug stability and how the parameters like temperature, pH, humidity and light can affect the drug stability. Physical pharmaceutics is very important subject which helps the researchers to design and formulate various dosage forms including its manufacturing aspects. The students will be proficient in handling various equipment used in physical pharmaceutics laboratory. The students will also be able to determine pKa, partition coefficient, surface tension, critical micelle concentration, HLB value, stability constant, buffer capacity, etc. in the laboratory. We have taken extra efforts to make the experiments simpler, easy to understand and perform. The graphs have also been provided wherever necessary. Each experiment is divided into sections like aim, practical significance, relevant course outcomes, practical skills, relevant affective domain related outcomes, practical outcomes, minimum theoretical background, requirements, related questions, and references. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. We are very much thankful to the designer, publisher, printers and all the stakeholders for putting their efforts for successfully bringing this manual out for the students. Hope this manual will help the students to learn the concept, principles and perform the experiments. We wish them all the best!!!

Pharmaceutics is a broad field which is connected to and focused on discovering, formulating, optimizing, and manufacturing various dosage forms, along with their standardization. One of the most important distinctions between Industrial Pharmacy and other branches of Pharmaceutics is the strict requirements of pharmaceutical industry for good manufacturing practice (GMP). To excel as a pharmaceutical formulator, you must be able to handle the increasingly complex risk-based GMP demands from early conceptual design, qualification and validation to practical developmental implementation and execution of a pharmaceutical quality system. Keeping the requirements of B. Pharm 1st semester pharmacy students in view, an effort has been taken to present 32 experiments in this book as per the requirement mentioned by PCI syllabus. All the experiments are presented with theory, principle, procedure, use and storage along with tabulations. I hope the students will like to utilize this book while performing the experiments for Industrial Pharmacy and will definitely get acquainted with the concepts with greater precision. The concerned faculties will definitely appreciate this book as a handbook to train their students. For the improvement of the quality of the Pharmaceutics I Laboratory Manual suggestions and criticisms from all corners of profession are greatly welcome. I would be grateful to the readers if they draw my attention to the deficiencies and errors that might have remained.

We are very pleased to put forth the revised edition of 'Laboratory Manual of Pharmaceutics'. We have incorporated all the suggestions, modified it to make it easier, student friendly and relevant in terms of achieving curriculum outcome. We are very much thankful to all the learned teachers who have given their feedback whole-heartedly. We have even incorporated the changes in this manual based on the feedback given by the teachers from all the institutes. Now, we believe that the manual has been fulfilling the aspirations of pharmaceutics teachers and students too. This manual is prepared as per PCI Education Regulations, 2020 for Diploma Course in Pharmacy. The procedures and formulas of all the experiments are reviewed and added, so that the advancement in the methods or apparatus can be addressed. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. We have also given the readings for the reference of students and better understanding. Moreover, assessment scheme is also given to help the student and teacher to know what to be assessed. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various topics of Pharmaceutics. The manual mainly includes the experiments through which the students will learn to prepare conventional dosage forms and few cosmetic formulations in the laboratory. Besides, experiments related to handling of Indian Pharmacopoeia and National formulary of India will make the students familiar with the Indian official compendiums. The demonstration based experiments will help the students to understand the tablet compression process and quality control test of tablets, capsules, emulsions and single-dose parenteral preparations. A brief introduction to various dosage forms before the related experiments can assist in better perception of the experiment. Each experiment is divided into sections like aim, practical significance, relevant professional competencies, relevant course outcomes, practical skills, relevant affective domain related outcomes, practical outcomes, minimum theoretical background, requirements, contents, marketed preparations, related questions, references and assessment scheme. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. Hope this manual will help the students to learn the concept, principles and perform the experiments virtually. We wish you all the best!!!

This practical book is designed for B. Pharmacy 1st semester students and is strictly as per the Pharmacy Council of India(PCI) regulations. This book aims to deliver fundamental knowledge on the basic pharmacy and with the science of preparing the different conventional dosage forms. It contains questions for internal and semester examinations which will help the students to prepare better for exams.

It has been great pleasure to give pharmacy students our book entitled “A Practical Manual of Pharmaceutics-I” as per the syllabus designed by Pharmacy Council of India (PCI), New Delhi. This book is very useful for First Year B. Pharm. Students of semester-I. This book has been organized into 10 chapters covering different pharmaceutical dosage forms. Also this book is useful for understanding dosage form along with their preparation methods, labeling, packaging and storage conditions in simple languages to fulfill the requirement of students. We feel short of words to express our thanks to Hon. Mr. Shrimant Dhole Sir, President of Jay Bhavanigad Vikas Pratishthan, Lakhewadi, Hon. Mrs. Chitralekha Dhole Madam, Vice-President of Jay Bhavanigad Vikas Pratishthan, Lakhewadi and Hon. Mr. Harshwardhan Khade Sir, Secretary of Jay Bhavanigad Vikas Pratishthan, Lakhewadi for their constant inspiration and moral support. We express our thanks to Dr. Samrat Khedkar Sir, Principal, JBVP’s Vidya Niketan College of Pharmacy, Lakhewadi and Dr. Swapnil Nazarkar Sir, HOD, JBVP’s Vidya Niketan College of Pharmacy, Lakhewadi for their continuous encouragement and guidance during publication of this book. We have gratitude for our beloved parents for their sustained support and encouragement throughout the journey. We express our thanks to JEC publication for publishing book on time. We are very much sure that this book is very useful to pharmacy students and teachers. Suggestions from readers of this practical manual for future improvement are always welcome.

We are very pleased to put forth the first edition of 'Laboratory Manual of Physical Pharmaceutics II'. This manual is prepared as per PCI Education Regulations, 2014 for Degree Course in Pharmacy. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various experiments in Physical Pharmaceutics II. The manual mainly includes the experiments through which the students will learn how the basic properties of drug like solubility, dissolution, can limit the bioavailability of drug and in turn the efficacy of the drug. The solubility enhancement techniques like reduction of particle size, use of solubilizing agents or prodrugs etc. are also discussed. The students will also learn about the importance of drug stability and how the parameters like temperature, pH, humidity and light can affect the drug stability. Physical pharmaceutics is very important subject which helps the researchers to design and formulate various dosage forms including its manufacturing aspects. The students will be proficient in handling various equipment used in physical pharmaceutics laboratory. The students will also be able to determine pKa, partition coefficient, surface tension, critical micelle concentration, HLB value, stability constant, buffer capacity, etc. in the laboratory. We have taken extra efforts to make the experiments simpler, easy to understand and perform. The graphs have also been provided wherever necessary. Each experiment is divided into sections like aim, practical significance, relevant course outcomes, practical skills, relevant affective domain related outcomes, practical outcomes, minimum theoretical background, requirements, related questions, and references. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. We are very much thankful to the designer, publisher, printers and all the stakeholders for putting their efforts for successfully bringing this manual out for the students. Hope this manual will help the students to learn the concept, principles and perform the experiments. We wish them all the best!!!

The book has been designed for pharmacy students as per the new syllabus (ER-2020) prescribed by Pharmacy Council of India (PCI). This book contains essential information that students gathered knowledge for formulation various dosage forms and prepare for competitive as well as annual or semester examination. Its primary objective is to provide knowledge about various formulation aspect which helpful for formulating a dosage form. This textbook has been written in easy language to ensure a lower reading level and understandable contents than ever. This book covers all major pharmaceutics dosage forms formulation. This book contains many chapters, each providing a description of various dosage forms formulation and their evaluation like syrup, suspension, emulsion, cream, ointment, lotion, lineaments, gel, tablets capsule, dusting powder, effervescent powder, injection, cosmetic preparation, evaluation of tablets, capsule, emulsion, parenteral products, and use of insulin pen, inhalers and spacer.

This book as per PCI Syllabus for Postgraduate Students [F. Y. M. Pharm. (Sem. II)] in Pharmaceutical Sciences will be important to investigate the understudy potential towards different novel drug delivery systems (NDDS) utilized in drug field, to accomplish the most extreme concentration of drug at the particular site of activity, to acquire adequate knowledge & skills to develop NDDS, to be aware of the criteria for the selection of drugs & polymers for the development of NDDS, to gain knowledge about cosmetics & cosmeceuticals with desired safety, stability & efficacy; in addition to explain information regarding the quantity of dose used in dosage form & to impart knowledge about targeted drug delivery system. The understudy will explain their logical commitment with central idea for the readiness of regular & novel medication conveyance framework for satisfaction of least prerequisite according to drug industry.