Written by pioneering experts in the field, this book offers a wide range of approaches for molecular imprinting, experimental protocols that exemplify specific techniques, and a detailed survey on molecular imprinting research and applications. It supplies a comprehensive tutorial for learning basic techniques and making new contributions to the field, as well as in-depth discussions, guidelines, and experimental protocols to help beginners gain a jump-start in the field of molecular imprinting. Molecularly Imprinted Materials: Science and Technology contains a multitude of experimental protocols illustrating specific techniques discussed in the text.

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Green Imprinted Materials provides a comprehensive overview of green aspects to MIPs. With a strong focus on food and environment, this book provides insights into the state-of-the-art and practice of green chemistry and its approaches to imprinting. Methodologies for the preparation of these materials, as well as their potential in developing sustainable separation and sensing processes in analytical and bioanalytical chemistry are critically discussed throughout the book. Future perspectives of green imprinting technology is also evaluated. This book is a valuable resource for researchers and graduate students in molecular imprinting science and technology and those interested in green chemistry and all those who wish to broaden their knowledge in the allied field. - Explores innovative strategies to materials science, molecular imprinting technology, polymer chemistry and green chemistry, as well as their applications for environmental, biological and food samples - Presents a plethora of novel and advantageous materials which have gathered the most pronounced attention over recent years - Provides state-of-the-art technologies and applications in MIP's and green chemistry

This book is divided into 5 sections starting with an historic perspective and fundamental aspects on the synthesis and recognition by imprinted polymers. The second section contains 8 up-to-date overview chapters on current approaches to molecular and ion imprinting. This is followed by two chapters on new material morphologies and in the last two sections various analytical applications of imprinted polymers are given, with the last four chapters devoted to the promising field of imprinted polymers in chemical sensors.The authors of this volume have widely different backgrounds; mainly polymer chemistry, organic chemistry, biochemistry and analytical chemistry, which means that this book has an interdisciplinary character and should appeal to a broad audience.

Molecularly Imprinted Polymers (MIPs): Commercialization Prospects guides the reader through the various steps in the conceptualization, design, preparation and innovative applications of molecularly imprinted polymers while also demystifying the challenges relating to commercialization. Sections cover molecularly imprinted polymers, design, modeling, compositions and material selection. Other sections describe novel methods and discuss the challenges relating to the use of molecularly imprinted polymers in specific application areas. The final chapters of the book explore the current situation in terms of patents and commercialized materials based on MIPs, as well as prospects and possible opportunities. This is a valuable resource for all those with an interest in the development, application, and commercialization of molecularly imprinted polymers, including researchers and advanced students in polymer science, polymer chemistry, nanotechnology, materials science, chemical engineering, and biomedicine, as well as engineers, scientists and R&D professionals with an interest in MIPs for advanced applications. - Covers all stages of molecular imprinting, from conceptualization, modeling, and solvent choice, to extraction, monomer composition and miniaturization - Offers a unique focus on commercialization, examining the current situation and addressing barriers to further commercialization - Includes state-of-the-art, novel approaches for the utilization of biopolymers and their nanoparticles as imprinting matrixes and numerical calculations in the design of MIPs

Controlled radical polymerization techniques for molecular imprinting, by Mark E. Byrne From bulk polymers to nanoparticles, by Lei Ye Post-imprinting and in-cavity functionalization, by Toshifumi Takeuchi Characterization of MIPs (affinity, selectivity, site heterogeneity...), by Richard Ansell Theoretical aspects and computer modelling, by Ian Nicholls MIPs in aqueous environments, by Bin Lu MIPs for binding macromolecules, by Kenneth J. Shea Solid phase extraction, by Ecevit Yilmaz Sensors, by Sergey A. Piletsky MIPs for catalysis and synthesis, by Marina Resmini Wastewater treatment, by Bo Mattiasson MIPs as tools for bioassays, biotransformation and drug delivery, by Meiping Zhao

The availability of materials that can bind selectively to a target molecule is the key to unlocking a host of new technologies. Molecular imprinting is an established technology, which allows the synthesis of materials containing highly specific receptor sites having an affinity for a target compound. For example, molecularly imprinted materials can mimic some of the functions of enzymes through the creation of three-dimensional cavities of specific size and shape for biorecognition of bioactive compounds. This volume offers a forum for technical exchange among members of the worldwide community of scientists and engineers who work in the area of molecular imprinting. Researchers from academia, government and industry present results in applications of molecular imprinting related to catalysis, combinatorial and computational methods, new monomers and recognition strategies, sensors, drug discovery and therapy, and new molecular imprinting formats.

Molecular imprinting is a rapidly growing field with wide-ranging applications, especially in the area of sensor development, where the process leads to improved sensitivity, reliability, stability, and reproducibility in sensing materials. Molecularly Imprinted Sensors in Analytical Chemistry addresses the most recent advances and challenges relating to molecularly imprinted polymer sensors, and is the only book to compile this information in a single source. From fundamentals to applications, this material will be valuable to researchers working in sensing technologies for pharmaceutical separation and chemical analysis, environmental monitoring and protection, defense and security, and healthcare. - Provides a systematic introduction to the different types of MIP-based sensors and reviews the basic principles behind each type of sensor - Includes state-of-the-art methodology supported by comparisons and discussions from leading experts in the field - Covers all types of sensing modes (optical, electrochemical, thermal, acoustic, etc.), materials and platforms - Appeals to a multidisciplinary audience of scientists and graduate students in a wide variety of fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering

This volume contains the proceedings of two symposia held at the 2002 MRS Spring Meeting in San Francisco. Molecular imprinting (MI) technology has attracted much attention and enjoyed tremendous development over the past decade. MI technology enables the preparation of materials with host sites that recognize specific guest molecules, analogous to the "lock-and-key" paradigm of antibodies and enzymes. Advantages of molecularly imprinted materials include: a degree of specificity approaching that of antibodies but with much greater temporal and thermal stability; rapid development because precise molecular design and chemical synthesis are unnecessary; and wide applicability because materials may be imprinted with almost any shape-persistent analyte of interest. Papers from Symposium M, "Molecularly Imprinted Materials, focus primarily on the fabrication of functional materials and devices based on MI materials. Studies are presented not only by experts in MI, but more importantly, by materials scientists integrating molecular imprinting with cutting-edge techniques in microfabrication and nanotechnology.