Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Green Imprinted Materials provides a comprehensive overview of green aspects to MIPs. With a strong focus on food and environment, this book provides insights into the state-of-the-art and practice of green chemistry and its approaches to imprinting. Methodologies for the preparation of these materials, as well as their potential in developing sustainable separation and sensing processes in analytical and bioanalytical chemistry are critically discussed throughout the book. Future perspectives of green imprinting technology is also evaluated. This book is a valuable resource for researchers and graduate students in molecular imprinting science and technology and those interested in green chemistry and all those who wish to broaden their knowledge in the allied field. - Explores innovative strategies to materials science, molecular imprinting technology, polymer chemistry and green chemistry, as well as their applications for environmental, biological and food samples - Presents a plethora of novel and advantageous materials which have gathered the most pronounced attention over recent years - Provides state-of-the-art technologies and applications in MIP's and green chemistry

Molecularly Imprinted Polymers (MIPs): Commercialization Prospects guides the reader through the various steps in the conceptualization, design, preparation and innovative applications of molecularly imprinted polymers while also demystifying the challenges relating to commercialization. Sections cover molecularly imprinted polymers, design, modeling, compositions and material selection. Other sections describe novel methods and discuss the challenges relating to the use of molecularly imprinted polymers in specific application areas. The final chapters of the book explore the current situation in terms of patents and commercialized materials based on MIPs, as well as prospects and possible opportunities. This is a valuable resource for all those with an interest in the development, application, and commercialization of molecularly imprinted polymers, including researchers and advanced students in polymer science, polymer chemistry, nanotechnology, materials science, chemical engineering, and biomedicine, as well as engineers, scientists and R&D professionals with an interest in MIPs for advanced applications. - Covers all stages of molecular imprinting, from conceptualization, modeling, and solvent choice, to extraction, monomer composition and miniaturization - Offers a unique focus on commercialization, examining the current situation and addressing barriers to further commercialization - Includes state-of-the-art, novel approaches for the utilization of biopolymers and their nanoparticles as imprinting matrixes and numerical calculations in the design of MIPs

This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Controlled radical polymerization techniques for molecular imprinting, by Mark E. Byrne From bulk polymers to nanoparticles, by Lei Ye Post-imprinting and in-cavity functionalization, by Toshifumi Takeuchi Characterization of MIPs (affinity, selectivity, site heterogeneity...), by Richard Ansell Theoretical aspects and computer modelling, by Ian Nicholls MIPs in aqueous environments, by Bin Lu MIPs for binding macromolecules, by Kenneth J. Shea Solid phase extraction, by Ecevit Yilmaz Sensors, by Sergey A. Piletsky MIPs for catalysis and synthesis, by Marina Resmini Wastewater treatment, by Bo Mattiasson MIPs as tools for bioassays, biotransformation and drug delivery, by Meiping Zhao

Higly efficient separation tools are increasingly required for satisfying the necessity of the modern society. In this context, for achieving optimized separation and purification of targeted compounds, the typical features of the imprinting technology and membrane science for developing the so-called imprinted membranes have been exploited. Imprinted membranes are smart systems endowing selective recognition properties towards specific molecules and ions that exhibit better performance with respect to the traditional separation techniques. The aim of this monography is to give a contribution in promoting the knowlegde on the current research trend about this topic. Starting from the concept of the molecular recognition the book introduces the reader to the fascinating world of the imprinting technology and membrane-based processes up to discussing the development of imprinted polymers as well as imprinted membranes, which represent their special format. The different imprinting strategies as well as the theory and mechanisms of the separation are also explained. Furthermore, the application of molecularly imprinted polymeric membranes in different areas for the selective recognition of drugs, active pharmaceutical ingredients, pesticides, other toxic compounds and proteins is discussed. The attention is also devoted to their employment in enantiomeric separation, sensors technology and controlled drug delivery. Finally, the production and application of ion imprinted membranes in the separation of metal ions, rare earth element and anions and the role of cyclodextrins in the imprinting technology are discussed.

Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry and related fields. - Introduces the most common functionalized nanomaterials and their morphologies, properties, and mechanisms for sensing applications - Reviews functionalization and fabrication methods and techniques for the integration of one- and two-dimensional materials for sensing applications - Addresses the most relevant applications of functionalized nanomaterials for biosensing and bioelectronics applications

Selected, peer reviewed papers from the 2011 International Conference on Chemical Engineering and Advanced Materials, (CEAM 2011), 28-30 May, 2011

Written by pioneering experts in the field, this book offers a wide range of approaches for molecular imprinting, experimental protocols that exemplify specific techniques, and a detailed survey on molecular imprinting research and applications. It supplies a comprehensive tutorial for learning basic techniques and making new contributions to the field, as well as in-depth discussions, guidelines, and experimental protocols to help beginners gain a jump-start in the field of molecular imprinting. Molecularly Imprinted Materials: Science and Technology contains a multitude of experimental protocols illustrating specific techniques discussed in the text.