This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. - Provides comprehensive overview of the potential role of polymeric systems in drug delivery - Explores the design, synthesis, and application of different smart material-based delivery systems - Includes fundamental and clinical applications

The book Ligand describes the diversity and versatility of ligands, covering structural features, donor-acceptor properties and secondary functions like molecular recognition. Moreover, this book also provides a comprehensive account on the applicability like catalysis, sensors, supramolecular assembly, photochemical property, bioinorganic chemistry, and so on. The advancement of fundamentals in ligand design and the control of physicochemical properties of coordination compounds has largely increased emphasis on understanding the structural and electronic features toward different perspectives in materials science. In this regard, this book has a special appeal to chemists, biologists and others. This book will be beneficial for the graduate students, teachers, researchers and other professionals who are interested to fortify and expand their knowledge in chemistry, biology, microbiology, biotechnology, materials science, environmental science and so on.

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Biopolymers are polymers produced by living organisms. Cellulose, starch, chitin, proteins, peptides, DNA and RNA are all examples of biopolymers. This book comprehensively reviews and compiles information on biopolymers in 30 chapters. The book covers occurrence, synthesis, isolation and production, properties and applications, modification, and the relevant analysis methods to reveal the structures and properties of some biopolymers. This book will hopefully be of help to many scientists, physicians, pharmacists, engineers and other experts in a variety of disciplines, both academic and industrial. It may not only support research and development, but be suitable for teaching as well.

This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Molecular imprinting focuses on the fabrication of an artificial receptor with perfect molecular recognition abilities. It has attracted a great deal of scientific attention because of the enormous opportunities it opens in the fields of separation, catalysis, and analysis. The advantages of the molecular imprinting enable to target a wide class of substances ranging from small molecules to big conglomerates, such as proteins or even cells. In recent years, sensor applications based on molecular imprinting have started to attract greater attention because of the easy creation of robust receptor sites with high specificity and sensitivity toward a target compound. A collection of contributions from distinguised experts, Handbook of Molecular Imprinting: Advanced Sensor Applications provides a comprehensive overview on the specific challenges of molecular imprinting in sensor applications. It covers various molecular imprinting approaches. As a result, a perspective of future device ensembles for sensing is acquired. The text lays particular emphasis on fundamental aspects as well as novel ideas in the context of sensor applications. It also highlights the operation principles of various sensor transducers that are generally employed in combination with molecular imprinting recognition elements.

Molecularly Imprinted Polymers (MIPs): Commercialization Prospects guides the reader through the various steps in the conceptualization, design, preparation and innovative applications of molecularly imprinted polymers while also demystifying the challenges relating to commercialization. Sections cover molecularly imprinted polymers, design, modeling, compositions and material selection. Other sections describe novel methods and discuss the challenges relating to the use of molecularly imprinted polymers in specific application areas. The final chapters of the book explore the current situation in terms of patents and commercialized materials based on MIPs, as well as prospects and possible opportunities. This is a valuable resource for all those with an interest in the development, application, and commercialization of molecularly imprinted polymers, including researchers and advanced students in polymer science, polymer chemistry, nanotechnology, materials science, chemical engineering, and biomedicine, as well as engineers, scientists and R&D professionals with an interest in MIPs for advanced applications. - Covers all stages of molecular imprinting, from conceptualization, modeling, and solvent choice, to extraction, monomer composition and miniaturization - Offers a unique focus on commercialization, examining the current situation and addressing barriers to further commercialization - Includes state-of-the-art, novel approaches for the utilization of biopolymers and their nanoparticles as imprinting matrixes and numerical calculations in the design of MIPs

Mip Synthesis, Characteristics and Analytical Application, Volume 86 in the Comprehensive Analytical Chemistry series, highlights advances in the field, with this new volume presenting interesting chapters on synthesis and polymerization techniques of molecularly imprinted polymers, Solid phase extraction technique as a general field of application of molecularly imprinted polymer materials, Advanced artificially receptor- based sorbents for solid phase extraction using molecular imprinting technology: a new trend in food analysis, Application of molecularly imprinted polymers in microextraction and solventless extraction techniques, Magnetic molecularly imprinted microspheres – analytical approach, Surface Imprinted Micro- and Nanoparticles, and much more. - Contains a valuable source of information on the wide spectrum of application fields of molecularly imprinted polymers as a green sorption medium - Describes the application potential of currently molecular imprinting technologies, associated with the solid phase extraction techniques, magnetic imprinted microspheres, sorbents in mass spectrometry, and imprinted polymer electrochemical sensors