Given the growing interest in the nutritional properties and health recommendations surrounding nut consumption, this book, Nut Consumption and its Usefulness in the Modern World, seeks to provide the most comprehensive presentation of current information available in the literature to enhance existing knowledge. The book is structured into four sections, each covering distinct aspects of nut research: Section 1 – “An Overview of Nuts” Section 2 – “Chemical Composition, Nutrients and the Beneficial Effects of Using Nuts” Section 3 – “The Use of Nuts for Medicinal Purposes” Section 4 – “Nut Contaminants”

This text provides readers with an in-depth understanding of the essential aspects of youth substance abuse—an important contemporary personal, social, and public health issue. Humans have been using natural and synthetic chemicals for at least two millennia—primarily for the purpose of treating medical problems, but also for recreational purposes. The 2014 Monitoring the Future survey of eighth, tenth, and twelfth grade students indicates a general decline in the use of illicit drugs over the last two decades. On the other hand, perceptions among youth that certain types of drug use—like marijuana and e-cigarettes—are harmless are growing. Youth Substance Abuse: A Reference Handbook provides an overview of the history and development of youth substance abuse along with a discussion of the medical, social, psychological, legal, and economic issues associated with youth substance abuse both in the United States and other parts of the world. The book begins with a comprehensive introduction to the subject of youth substance abuse that explains how modern societies have reached the point where abuse of both legal and illegal substances is a major health issue in many nations. Readers will learn about the effects of substances such as cocaine, marijuana, and heroin as well as substances that are typically legal but have deleterious health, social, or psychological effects, such as tobacco, alcohol, prescription drugs, and electronic cigarettes. Subsequent chapters address how and why youth substance abuse has become a problem in the United States and other countries, the demographics of this widespread problem, the direct and indirect effects of youth substance abuse and addiction, and the range of services and methods that are available for treating substance abuse.

Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator's fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist's early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. - Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property - Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape - Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery - Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry

Substance use and substance use disorders (SUDs) have been documented in a number of cultures since the beginnings of recorded time and represent major societal concerns in the present day. The Oxford Handbook of Substance Use and Substance Use Disorders provides comprehensive reviews of key areas of inquiry into the fundamental nature of substance use and SUDs, their features, causes, consequences, course, treatment, and prevention. It is clear that understanding these various aspects of substance use and SUDs requires a multidisciplinary perspective that considers the pharmacology of drugs of abuse, genetic variation in these acute and chronic effects, and psychological processes in the context of the interpersonal and cultural contexts. Comprising two volumes, this Handbook also highlights a range of opportunities and challenges facing those interested in the basic understanding of the nature of these phenomena and novel approaches to assess, prevent, and treat these conditions with the goal of reducing the enormous burden these problems place on our global society. Chapters in Volume 1 cover the historical and cultural contexts of substance use and its consequences, its epidemiology and course, etiological processes from the perspective of neuropharmacology, genetics, personality, development, motivation, and the interpersonal and larger social environment. Chapters in Volume 2 cover major health and social consequences of substance involvement, psychiatric comorbidity, assessment, and interventions. Each chapter highlights key issues in the respective topic area and raises unanswered questions for future research. All chapters are authored by leading scholars in each topic. The level of coverage is sufficiently deep to be of value to both trainees and established scientists and clinicians interested in an evidenced-based approach.

​This book is intended as a one-stop reference that will assist primary care community dentists, sports physicians, athletic trainers, and emergency room physicians in meeting the needs of athletes when managing facial and dental trauma and sports-related oral diseases. The opening chapters provide a complete review of sports-related dentoalveolar trauma, with coverage of emergent care, the role of endodontics, surgical issues, and restorative considerations. Prevention of dental trauma by means of mouthguards is then examined, with attention to materials and design, public policy concerning the use of mouthguards, and the role of mouthguards in relation to the ever more pressing issue of concussion in sport. Dental erosion in athletes, for example due to energy drinks, is discussed, as are the possible sequelae of use of spit tobacco, performance-enhancing drugs, and ergogenic aids. The new topic of the potential value of dental appliances in enhancing sports performance is also addressed. The book concludes by reviewing the role of the dentist within the multidisciplinary sports medicine team. The text is supported by an abundance of informative illustrations.

The book presents guides to the diagnosis and management of Oral Submucous Fibrosis, and includes a concise update on the recent evidence on aetiology and aetiopathogenesis to educate the reader on the prevention of the disease. Oral Submucous Fibrosis is a potentially malignant disorder that leads to the development of oral cancer. The first part of the book is dedicated to the epidemiology, the clinical features and the classification of Oral Submucous Fibrosis and associated conditions. The aetiology of Oral Submucous Fibrosis including lifestyle and genetic factors is discussed in the second part of the book followed by two chapters on the etiopathogenesis of the disease. Readers will find clear guidance on investigative techniques and the management of Oral Submucous Fibrosis. The last part of the book considers the connection between Areca nut and the disease and outlines methods of supporting areca nut chewers on habit cessation. The book is designed to serve as a comprehensive resource and reference in the oral health domain for learners at all levels, researchers, clinicians, and public health professionals. It will be of great value for students and trainees on any graduate program in dentistry.

This volume celebrates the life and career of Gordon Rausser, pioneer and leader in natural resource economics, while critically overviewing the emerging literature in the field. As the chair of the Agriculture and Resource Economics department at UC Berkeley, Rausser led the transformation of the department from a traditional agricultural economics department to a diverse resource economics department addressing issues of agriculture, food, natural resources, environmental economics, energy, and development. This book builds on this theme, showcasing not only the scope of Rausser's work but also key developments in the field. The volume is organized into two parts. The first part speaks about the lessons of Gordon Rausser's career, in particular, his role as a leader in different spheres, his capacity to integrate teaching and entrepreneurship, and his impact on the world food system. The second part will address some of the significant developments in the field he contributed to and how it relates to his work. The chapters include contributions from modern leaders in the economics field and cover diverse topics from many subfields including public policy, public finance, law, econometrics, macroeconomics, and water resources. Providing an excellent reference, as well as a celebration of a pivotal figure in the field, this volume will be useful for practitioners and scholars in agricultural and resource economics, especially the many individuals familiar with Gordon Rausser and his career.

Nuts and dried fruits are part of our daily diet. They are consumed whole or as ingredients of many food products such as muffins, cereals, chocolates, energy bars, breads, and cookies, among others. Health Benefits of Nuts and Dried Fruits provides a comprehensive overview of the literature on the health benefits of nuts and dried fruits. The book summarizes the current state of knowledge in key research areas and provides ideas for future scientific research and product development. Nuts, a term that comprises tree nuts and peanuts, are highly nutritious, containing health-promoting macronutrients, micronutrients, vitamins, and bioactive phytochemicals; they are one of the edible foods with the highest content in antioxidants. The consumption of nuts is recognized for its health-promoting properties, which ranges from a consistent cholesterol-lowering effect in clinical trials to a robust association with reduced risk of cardiovascular disease and all-cause mortality in prospective studies. In spite of the high energy content of nuts, there is no evidence that their frequent consumption promotes obesity, and they may even help control it. Dried fruits, which serve as important healthful snacks worldwide, are nutritionally equivalent to fresh fruits while providing all of their bioactive components in concentrated form. While the evidence level concerning the health effects of dried fruits lags behind that on nuts, it suggests that individuals who consume dried fruits regularly have a lower risk of cardiovascular disease, obesity, and other non-communicable diseases. Main features of the book concerning nuts and dried fruits: • Provides detailed information on health effects • Highlights current regulation and health claims • Provides updated dietary recommendations • Describes nutrient absorption and metabolism • Discusses mechanisms implicated in the health effects Although this book is intended primarily as a reference, by comprehensively reviewing the current state of knowledge it can guide future research on the topic. Among others, food scientists, biochemists, nutritionists, health professionals, decision makers, and regulatory agencies can draw much benefit from its contents. Hopefully, it will help in public health strategies to promote healthy aging and improve population wellbeing.

The world's most comprehensive, well documented, and well illustrated book on this subject. With extensive subject and geographic index. 245 photographs and illustrations - mostly color. Free of charge in digital format on Google Books

The world's most comprehensive, well documented, and well illustrated book on this subject. With extensive subject and geographical index. 108 photographs and illustrations - many color. Free of charge in digital PDF format on Google Books.