There have been tremendous advancements in the Pharmacology of Infectious Diseases in recent years. These recent advancements underline the importance of a multidisciplinary approach in the study of infectious diseases. In order to explore this fast-growing area, Frontiers is launching a new series of Research Topics focusing on the evolution of methods, processes, scientific breakthroughs and technology advances in the field of Pharmacology of Infectious Diseases. In this article collection, we seek contributions exploring the changing context, the recent advances, the challenges, and the emerging new perspectives within the field.

Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters

With recent updates, the second edition of Evolutionary Medicine presents general principles of evolutionary biology and organismal design, then applies them to medical issues where these principles bring useful insights.

This book approaches the past, present, and future of human physiology and diseases from the perspective of Darwin’s evolutionary theory. In addition to natural, sexual, and artificial selection, the book emphasizes the maladaptation of human physiology and resultant modern diseases, including pandemics, obesity, diabetes, and hypertension. It highlights the role of evolutionary genomics in the discovery of hormones and signaling molecules that can act as new drugs and the use of bionics in medical tool design. Tumor formation, metastasis, and therapies are also explained through evolutionary principles. In addition, cultural meme mutations and selection explain the evolution of language, fashion, religion, and more.

Neurocognitive and neuropsychiatric disorders contribute to a substantial amount of global morbidity and, as such, the identification of their causes is paramount to understanding their underlying pathophysiology as well as treatment and prevention strategies. Infectious Diseases in Neurocognitive and Neuropsychiatric Medicine considers the many infectious diseases that have been associated with cognitive and neuropsychiatric function. In Parts I-III, each chapter focuses on a different disease to cover a range of viral, bacterial, and parasitic diseases in neurocognitive and neuropsychiatric medicine. Part IV considers infectious diseases and clinical conditions and syndromes, while Part V examines the relationship between neurocognitive and neuropsychiatric function and the microbiome and Part VI the relationship with childhood development. In addition to molecular and clinical descriptions of the infectious diseases themselves, many chapters also explore the diseases' basic epidemiological features to consider where they may be exerting the greatest impact on cognitive and neuropsychiatric function. Where they exist, the possible mitigating factors and treatments for the neuropsychiatric and cognitive dysfunction that can be associated with these infectious diseases are also explored. In doing so, this volume examines the neurocognitive and neuropsychiatric disorders associated with infectious disease to better understand the role infections play.

Evolutionary medicine has been steadily gaining recognition, not only in modern clinical research and practice, but also in bioarchaeology (the study of archaeological human remains) and especially its sub-discipline, palaeopathology. To date, however, palaeopathology has not been necessarily recognised as particularly useful to the field and most key texts in evolutionary medicine have tended to overlook it. This novel text is the first to highlight the benefits of using palaeopathological research to answer questions about the evolution of disease and its application to current health problems, as well as the benefits of using evolutionary thinking in medicine to help interpret historical disease processes. It presents hypothesis-driven research by experts in biological anthropology (including palaeopathology), medicine, health sciences, and evolutionary medicine through a series of unique case studies that address specific research questions. Each chapter has been co-authored by two or more researchers with different disciplinary perspectives in order to provide original, insightful, and interdisciplinary contributions that will provide new insights for both palaeopathology and evolutionary medicine. Palaeopathology and Evolutionary Medicine is intended for graduate level students and professional researchers in a wide range of fields including the humanities (history), social sciences (anthropology, archaeology, palaeopathology, geography), and life sciences (medicine and biology). Relevant courses include evolutionary medicine, evolutionary anthropology, medical anthropology, and palaeopathology.

Cutting edge technology-based drug delivery systems have been rapidly growing and are being applied to various sections of biomedicine. The current scenario of global burden due to infectious disorders can take advantage of nanoparticulate based carriers to advance the cure efficiency. Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with introduction about infectious diseases and its global burden. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. Nanostructured Drug Delivery Systems in Infectious Disease Treatment is a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases. - Focuses on the application of different nanotechnology-based drug delivery systems - Offers information on how to design and develop the nanotechnology-based drug delivery systems and devices for the treatment of infectious disorders - Explores challenges and regulatory concerns of nanomedicine in infectious disorders

The Reviews in Antibiotic Resistance and New Antimicrobial Drugs will publish high-quality scholarly review papers on key topics in antibiotic resistance and new antimicrobial drugs. It aims to highlight recent advances in the field, whilst emphasizing important directions and new possibilities for future inquiries. We anticipate the research presented will promote discussion in the antibiotic resistance and new antimicrobial drugs community that will translate to best practice applications in clinical, public health, and policy settings.

Lack of clean water, inadequate sanitation, and insufficient infection prevention and control promote the spread of parasites. The discovery of antiparasitic drugs was considered a milestone in the veterinary and medical sciences, but their use has subsequently become limited due to the emergence of resistance. While plenty of attention has been given in human and animal health communities to the global threat of antimicrobial drug resistance, specific antiparasitic advice is less available. This book provides an in-depth view of the issue for parasitologists, pharmacologists and veterinary scientists. Specifically discussing antiparasitic drug resistance mechanisms and factors responsible for the problem.