Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts.* Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions.* New, detailed information on the pathogenesis and immunology of the Flavivirus family.* Descibes the technologies that have contributed to our current knowledge about the Flaviviruses.* Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease.* An exhaustive compendium of current and past knowledge on the Flavivirus family

Encephalitis is an inflammation of the brain tissue associated with clinical evidence of brain dysfunction. The disease is of high public health importance worldwide due to its high morbidity and mortality. Flaviviruses, such as tick-borne encephalitis virus, Japanese encephalitis virus, Murray Valley encephalitis virus, or St. Louis encephalitis virus, represent important causative agents of encephalitis in humans in various parts of the world. The book Flavivirus Encephalitis provides the most recent information about selected aspects associated with encephalitic flaviviruses. The book contains chapters that cover a wide spectrum of subjects including flavivirus biology, virus-host interactions, role of vectors in disease epidemiology, neurological dengue, and West Nile encephalitis. Special attention is paid to tick-borne encephalitis and Japanese encephalitis viruses. The book uniquely combines up-to-date reviews with cutting-edge original research data, and provides a condensed source of information for clinicians, virologists, pathologists, immunologists, as well as for students of medicine or life sciences.

Presents a comprehensive review of cell-mediated immunity to viral infection, highlighting aspects relevant to HIV research. Opening chapters discuss antigen processing and presentation, and lymphokine function. Subsequent chapters consider immune responses to individual viruses including: HIV, visn

Offering up-to-date coverage of familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease, as well as viruses that are almost unknown in most developed nations, Zika and Other Neglected and Emerging Flaviviruses brings together information that allows for easy comparison of similarities and differences of this viral group in a single, convenient volume. Each chapter includes a brief Introduction, history, the diseases, the virus, the immune response, prevention or treatment, an extensive list of references, and a summary overview. The book concludes with a chapter tying together information about flaviviruses and other potential new microbial threats. - Covers familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease (such as Zika, dengue and West Nile viruses), as well as lesser-knowns viruses such as tick-borne encephalitis virus, Powassan virus, Omsk hemorrhagic fever, and Murray Valley encephalitis virus. - Allows health-related personnel to search for potential treatments and protective responses by examining what measure did or did not work with other, related flaviviruses. - Helps readers understand how to prevent or contain newly emerging viral threats—a particularly timely topic regarding the global spread of COVID-19 and the potential of tick-borne encephalitis to rapidly spread and cause severe illness, panic, and disruption of economies. - Consolidates today's available information on this timely topic into a single, convenient resource.

Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

The new edition of this popular text presents microbiology in a succinct, easy-to-use, and engaging manner. Clear discussions explain how microbes cause disease in humans, and review the updated vaccines and new antibiotics currently available to treat these diseases. Expert coverage of basic principles, the immune response, laboratory diagnosis, bacteriology, virology, mycology, and parasitology ensures that you'll understand all the facts vital to the practice of medicine today. A revised artwork program illustrates the appearance of disease, simplifying complex information, while text boxes and additional summary tables emphasize essential concepts and learning issues for more efficient exam review. Online access to Student Consult-where you'll find the complete contents of the book, fully searchable...Integration Links to bonus content in other Student Consult titles...updated features for both students and instructors...and much more-further enhances your study and exponentially boosts your reference power. Focuses on why the biologic properties of organisms are important to disease in humans, equipping you with a practical understanding of microbiology. Examines etiology, epidemiology, host defenses, identification, diagnosis, prevention, and control for each microbe in consistently organized chapters, enabling you to find the information you need fast. Features summary tables and text boxes that emphasize essential concepts and learning issues, enabling you to make your exam review more efficient. Correlates basic science with clinical practice through review questions at the end of each chapter to help you understand the clinical relevance of the organisms examined. Uses clinical cases from literature reports to illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Features revised artwork-more than 635 brilliant images, nearly all in full color-that offers a more consistent and modern approach to the study of medical microbiology. Provides more clinical photographs throughout that help you better understand the clinical applications of microbiology. Offers expanded use of summary boxes for bacteria throughout all organism chapters to further enhance your review and learning. Includes enhanced Student Consult features including self-assessment questions, clinical cases, animations showing the actions of various important toxins, and a PowerPoint presentation with supplemental images of organisms and stains. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Quickly learn the microbiology fundamentals you need to know with Medical Microbiology, 7th Edition, by Dr. Patrick R. Murray, Dr. Ken S. Rosenthal, and Dr. Michael A. Pfaller. Newly reorganized to correspond with integrated curricula and changing study habits, this practical and manageable text is clearly written and easy to use, presenting clinically relevant information about microbes and their diseases in a succinct and engaging manner. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Master the essentials of medical microbiology, including basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology. Progress logically through consistently formatted chapters that examine etiology, epidemiology, disease presentation, host defenses, identification, diagnosis, prevention, and control for each microbe. Grasp complex material quickly with summary tables and text boxes that emphasize essential concepts and issues. Learn the most up-to-date and relevant information in medical microbiology. Study efficiently thanks to a reorganized format that places review chapters at the beginning of each section and review questions at the end of each chapter. Focus on clinical relevance with new interactive case presentations to introduce each of the microbial pathogens that illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Visualize the clinical presentations of infections with new and updated clinical photographs, images, and illustrations.

The publication of this volume of The Viruses entitled The Togaviridae and Flaviviridae comes at an appropriate time. The structure and rep lication strategies of these viruses are now known to be sufficiently di verse to warrant the removal of flaviviruses from the Togaviridae family and establish them as an independent family. Flaviviridae have a special place in the history of virology. The prototype virus-yellow fever virus was the first virus to be identified as the cause of a human disease. Some of the history of this discovery is described in Chapter 1 of this volume; in Chapter 10 the complete sequence of the RNA genome of the virus is presented. This sequence not only defines the primary structure of the viral proteins, it also clarifies the mechanism of translation of the fla vivirus genome. Knowledge of the sequence of the structural proteins of these viruses represents an important step in the potential goal of using purified flavivirus glycoproteins as vaccines. Many of the chapters in this volume focus on the structure and replication of the Togaviridae. These viruses have provided valuable models for studies in cell biology, partic ularly with regard to the cotranslational and posttranslational steps re quired for the synthesis and localization of membrane glycoproteins. Fur thermore, Togaviridae have been pivotal in our growing understanding of how enveloped viruses enter and exit from cells. The broad outlines of the structure and gene expression of Togavir idae and Flaviviridae are known, but important questions remain.

This book provides trajectories and illustrations of viruses that have catapulted into the global arena (linked to humans, animals, and vectors) due to human behaviors in recent years, as well as viruses that have already shown expansion among humans, animals, and vectors just a few decades ago. Topics in the current book include: vaccines environmental impact emerging virus transmission Filovirus (Ebola) hemorrhagic fevers flaviviruses Dengue evasion papillomaviruses Hepatitis C Nipah virus giant viruses hantaviruses bunyaviruses encephalitides West Nile virus Zika virus XMRV henipaviruses human respiratory syncytial virus influenza A virus several aspects of HIV-1

Fenner's Veterinary, Virology, Fourth Edition, is the long awaited new edition of Veterinary Virology, 3e, which was published in 1999. Fully revised and updated by the new author team, part I presents the fundamental principles of virology related to animal infection and disease, and part II addresses the clinical features, pathogenesis, diagnosis, epidemiology and prevention of individual diseases. New to this Edition - New author team - one main author to ensure that the book reads like an authored book but with the benefit of using experts to contribute to specific topics - Text has been refocused - part I has been condensed and where appropriate incorporated into part II to make it more user friendly - The number of figures have been increased and are now in full color - Fully revised and updated to include the latest information in the field of veterinary virology - Beautifully illustrated color figures throughout - Organized and current information provided by an expert team of authors