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Diagnosis and Treatment in Internal Medicine equips trainee doctors with the essential skills and core knowledge to establish a diagnosis reliably and quickly, before outlining the management of the clinical condition diagnosed. Organised into three sections, the first provides a vital overview, whilst the second focuses on common presentations and diagnoses. Uniquely, this new book shows readers how to turn symptoms into a list of diagnoses ordered by probability - a differential diagnosis. Experienced consultants who teach trainees every day demonstrate how to derive an ordered differential diagnosis, how to narrow this down to a single diagnosis and if not, how to live with diagnostic uncertainty. The final section provides a comprehensive account of the management of system-based syndromes and diseases. Highly-structured chapters emphasize how common conditions present, how to approach a diagnosis, and how to estimate prognosis, treatment and its effectiveness. An onus is placed on the development of crucial diagnostic skills and the ability to devise evidence-based management plans quickly and accurately, making this an ideal text for core medical trainees.

This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.

The third edition of Pediatric Allergy continues this title's steadfast tradition of providing comprehensive, authoritative guidance on the day-to-day diagnosis and management of pediatric allergic and immunologic diseases. You'll have the most up-to-date research at hand thanks to an easily accessible full-color format that highlights a host of new chapters, extensive updates, and clinically focused coverage. Whether you're a student, resident, pediatrician or allergist, you'll appreciate this user-friendly and versatile source for providing optimal care! Includes diagnostic tests available for asthma, upper respiratory allergy, and more. Equips you with an understanding of the immune mechanisms underlying allergic diseases. Features coverage of drug allergies and cross-reactivity. Highlights clinical pearls discussing the best approaches to the care and treatment of pediatric patients. Appendices listing common food allergies and autoantibodies in autoimmune diseases make for quick reference to essential material. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Revised asthma section examines current asthma guidelines; school-centered asthma programs; exercise-induced asthma; and new directions in asthma therapy. Includes the most current knowledge relating to emerging asthma within young children, medication adherence, and the impact of infection on the natural history of asthma. New information on gene therapy, stem-cell therapy, and a host of new immunodeficiency diseases helps you obtain the best results from the therapeutics for pediatric allergic and immunologic diseases. Features brand-new chapters on immunopathology; diagnostics and management; potential immunotherapeutic strategies for treating food allergies; current status of immunotherapy for food allergy; and biologic therapies. Focused coverage of today's hot topics in pediatric allergy includes the use of targeted biologics to treat specific activation pathways leading to severe allergic diseases; defects of innate immunity; rheumatic diseases of childhood; and inflammatory disorders. Discusses new studies examining potential etiologies for the increase in food allergy and examines potential immunotherapeutic strategies for treating food allergies. New evidence-based principles of medical care help you make the best use of available medications for your patients.